DrugRepV_0186 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Zika virus | Mex2-81 | NA | TCID50 assay | Decrease (80 %) | Approved | 28099856 |
DrugRepV_0187 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Zika virus | Mex2-81 | NA | TCID50 assay | Decrease (75 %) | Approved | 28099856 |
DrugRepV_0188 | Mycophenolic Acid | Antineoplastic and Immunomodulating Agents | Organ rejection (immunosuppressants) | Zika virus | Mex2-81 | NA | TCID50 assay | Decrease (95 %) | Approved | 28099856 |
DrugRepV_0189 | Cabozantinib | Antineoplastic and Immunomodulating Agents | Cancer | Zika virus | Mex2-81 | NA | TCID50 assay | No significant effect (30 %) | Approved | 28099856 |
DrugRepV_0190 | Cabozantinib | Antineoplastic and Immunomodulating Agents | Cancer | Zika virus | Mex2-81 | NA | TCID50 assay | Decrease (75 %) | Approved | 28099856 |
DrugRepV_0191 | Cabozantinib | Antineoplastic and Immunomodulating Agents | Cancer | Zika virus | Mex2-81 | NA | TCID50 assay | No significant effect (0 %) | Approved | 28099856 |
DrugRepV_0192 | Nanchangmycin | Antibacterial; Antiviral | NA | Chikungunya virus | Mex2-81 | NA | TCID50 assay | Decrease (90 %) | NA | 28099856 |
DrugRepV_0193 | Nanchangmycin | Antibacterial; Antiviral | NA | Chikungunya virus | Mex2-81 | NA | TCID50 assay | Decrease (95 %) | NA | 28099856 |
DrugRepV_0194 | Nanchangmycin | Antibacterial; Antiviral | NA | Chikungunya virus | Mex2-81 | NA | TCID50 assay | Decrease (95 %) | NA | 28099856 |
DrugRepV_0195 | Tenovin-1 | Anticancer | Cancer | Zika virus | Mex2-81 | NA | TCID50 assay | No significant effect (40 %) | NA | 28099856 |
DrugRepV_0196 | Tenovin-1 | Anticancer | Cancer | Zika virus | Mex2-81 | NA | TCID50 assay | No significant effect (50 %) | NA | 28099856 |
DrugRepV_0197 | Tenovin-1 | Anticancer | Cancer | Zika virus | Mex2-81 | NA | TCID50 assay | Decrease (75 %) | NA | 28099856 |
DrugRepV_0262 | Imatinib | Antineoplastic and Immunomodulating Agents | Leukemia | Myelodysplastic/myeloproliferative disease | Gastrointestinal stromal tumors | Severe acute respiratory syndrome coronavirus | MA15 | NA | TCID50 assay | Decrease (>100 Fold) | Approved | 27466418 |
DrugRepV_0263 | Imatinib | Antineoplastic and Immunomodulating Agents | Leukemia | Myelodysplastic/myeloproliferative disease | Gastrointestinal stromal tumors | Middle East respiratory syndrome coronavirus | Hu/Jordan-N3/2012 | NA | TCID50 assay | Decrease (~20 Fold) | Approved | 27466418 |
DrugRepV_0264 | Imatinib | Antineoplastic and Immunomodulating Agents | Leukemia | Myelodysplastic/myeloproliferative disease | Gastrointestinal stromal tumors | Severe acute respiratory syndrome coronavirus | MA15 | NA | TCID50 assay | Decrease (>10 Fold) | Approved | 27466418 |
DrugRepV_0265 | Imatinib | Antineoplastic and Immunomodulating Agents | Leukemia | Myelodysplastic/myeloproliferative disease | Gastrointestinal stromal tumors | Middle East respiratory syndrome coronavirus | Hu/Jordan-N3/2012 | NA | TCID50 assay | Decrease (>100 Fold) | Approved | 27466418 |
DrugRepV_0305 | Dinaciclib | Anticancer | Cancer | Influenza virus | A/Mississippi/3/01 wt | | TCID50 assay | Decrease (1.5 Log10 virus titer (TCID50/ml)) | Investigational | 26192013 |
DrugRepV_0306 | Dinaciclib | Anticancer | Cancer | Influenza virus | A/Mississippi/3/01 H275Y | | TCID50 assay | Decrease (>1 Log10 virus titer (TCID50/ml)) | Investigational | 26192013 |
DrugRepV_0307 | Flavopiridol | Anticancer | Esophageal cancer | Leukemia (lymphoid) | Lung cancer | Liver cancer | Influenza virus | A/Mississippi/3/01 wt | | TCID50 assay | Decrease (1.5 Log10 virus titer (TCID50/ml)) | Experimental, Investigational | 26192013 |
DrugRepV_0308 | Flavopiridol | Anticancer | Esophageal cancer | Leukemia (lymphoid) | Lung cancer | Liver cancer | Influenza virus | A/Mississippi/3/01 H275Y | | TCID50 assay | Decrease (~1 Log10 virus titer (TCID50/ml)) | Experimental, Investigational | 26192013 |
DrugRepV_0309 | PIK-75 | NA | NA | Influenza virus | A/Mississippi/3/01 wt | | TCID50 assay | Decrease (~1 Log10 virus titer (TCID50/ml)) | NA | 26192013 |
DrugRepV_0310 | PIK-75 | NA | NA | Influenza virus | A/Mississippi/3/01 H275Y | | TCID50 assay | Decrease (~1 Log10 virus titer (TCID50/ml)) | NA | 26192013 |
DrugRepV_0740 | Probenecid | Musculo-Skeletal System | Gout | Influenza virus | A/WSN/33 | | TCID50 assay | Decrease (>3 Log10 TCID50) | Approved, Investigational | 23129053 |
DrugRepV_0741 | Probenecid | Musculo-Skeletal System | Gout | Influenza virus | A/New/ Caledonia/20/99 | | TCID50 assay | Decrease (2 Log10 TCID50) | Approved, Investigational | 23129053 |
DrugRepV_0742 | Probenecid | Musculo-Skeletal System | Gout | Influenza virus | A/California/04/09 | | TCID50 assay | Decrease (>1 Log10 TCID50) | Approved, Investigational | 23129053 |
DrugRepV_5267 | 25-Hydroxycholesterol | NA | NA | Lassa virus | Josiah | NA | TCID50 assay | Decrease (>1.1 Log) | Experimental | 27999160 |
DrugRepV_5268 | 25-Hydroxycholesterol | NA | NA | Lassa virus | Josiah | NA | TCID50 assay | Decrease (1.4 Log) | Experimental | 27999160 |
DrugRepV_5269 | Favipiravir | Antiviral | Influenza virus | Lassa virus | Josiah | NA | TCID50 assay | Decrease (90 %) | Investigational | 26456301 |
DrugRepV_5270 | Favipiravir | Antiviral | Influenza virus | Lassa virus | Josiah | NA | TCID50 assay | Decrease (90 %) | Investigational | 26456301 |
DrugRepV_5420 | Losmapimod | NA | Chronic Obstructive Pulmonary Disease | Lassa virus | Josiah | NA | TCID50 assay | Decrease (50 %) | Investigational | 30953674 |
DrugRepV_5506 | Anthralin | NA | Psoriasis | Influenza virus | H1N1 | | TCID50 assay | Decrease (99 %) | Approved | 32132985 |
DrugRepV_5507 | Anthralin | NA | Psoriasis | Influenza virus | H1N1 | | TCID50 assay | Decrease (99 %) | Approved | 32132985 |
DrugRepV_6424 | Carbenoxolone disodium | NA | Digestive tract ulcers | Dengue virus | Hawaii | | TCID50 assay | Decrease (500 Fold) | Experimental | 27155198 |
DrugRepV_6425 | Carbenoxolone disodium | NA | Digestive tract ulcers | Dengue virus | New Guinea C | | TCID50 assay | Decrease (2000 Fold) | Experimental | 27155198 |